Fig. 8
KDM5C plays important roles in morphogenesis and organ development. RT-PCR analysis of genes (with high fold-change values) selected after RNA sequence analysis. Expression levels of sox8, sox10, and wnt8a were significantly reduced in kdm5c morphants. Additionally, downregulation of ephA4, ephA2, efnb2, and aldh1a2 (genes associated with eye development) was observed as a result of kdm5c knockdown. CTL, control