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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: From compartments to loops: understanding the unique chromatin organization in neuronal cells

Fig. 2

Differences in chromatin organization between neuronal and non-neuronal brain cell types at various chromatin organization levels. A The main features of chromatin organization in non-neuronal brain cells: strong compartmentalization, a lower density of TADs, and shorter chromatin loops. B Characteristics of chromatin organization in neurons: weaker compartmentalization, an increased density of TADs, and extended chromatin loops. C A hallmark of neuronal chromatin organization: neuron-specific long-range chromosomal interactions mediated by Polycomb Group (PcG) proteins

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