Table 2 Number of age-associated CpG sites identified in each tissue type passing false-discovery rate (FDR) 0.05
From: DNA methylation correlates of chronological age in diverse human tissue types
Tissue | Age-associated CpG sites (P-value threshold) | ||
|---|---|---|---|
Hypermethylated | Hypomethylated | Total | |
Lung (n = 223) | 29,432 (0.003) | 21,422 (0.003) | 50,084 (0.003) |
Colon (n = 223) | 40,029 (0.004) | 17,140 (0.004) | 57,169 (0.004) |
Ovary (n = 157) | 96,210 (0.009) | 38,776 (0.009) | 134,986 (0.009) |
Prostate (n = 119) | 15,624 (0.002) | 15,220 (0.002) | 30,844 (0.002) |
Whole blood (n = 54) | 109 (3.5e-5) | 438 (3.6e-5) | 547 (3.5e−5) |
Testis (n = 50) | 1,278 (3.4e-4) | 3,786 (3.4e-4) | 5,064 (3.4e−4) |
Kidney (n = 50) | 41 (2.7e-6) | 0 (NA) | 41 (2.7e−6) |
Muscle (n = 47) | 0 (NA) | 0 (NA) | 0 (NA) |
Breast (n = 38) | 24,766 (0.003) | 13,220 (0.003) | 37,986 (0.003) |