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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Long-term exposure to diesel exhaust particles induces concordant changes in DNA methylation and transcriptome in human adenocarcinoma alveolar basal epithelial cells

Fig. 1

A Number of differentially methylated CpG sites (DMCs) after 4 weeks of exposure to diesel exhaust particles (DEP) as a function of DEP concentration. DMCs were obtained from differential methylation analysis using DNA methylation from A549 cells treated with 0 (n = 3), 3 µg/ml (n = 3), 10 µg/ml (n = 2), and 30 µg/ml (n = 2) concentrations of DEP. B Violin plot of β-values at DMCs as a function of DEP concentration. The blue line connects the mean β-values in each group. C–D Scatter plots (with linear regression and regression equation) showing the relationship between the DNA methylation levels of the respective groups at each DMC. For each DMC, ∆Mi = Mi - Mcontrol, where i = 3, 10, 30 µg/ml DEP

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Epigenetics & Chromatin

ISSN: 1756-8935