Fig. 4

Detailed annotation analysis of LINE and LTR subfamilies in F2 embryos. A and D) Violin plots of average methylation levels of all CpGs in each subfamily in LINE and LTR. Bold lines represent medians and thin lines represent quartiles. The differences in the methylation levels between the control and arsenic group were tested by Welch’s t test. B and E) Distribution (%) of LINE and LTR subfamilies among all CpGs (gray bars) and among all DMCs (hypoDMCs (black bars) plus hyperDMCs (white bars)), respectively. Please see the legend in Fig. 3 for the method of statistics. C) The positions of hypo- and hyper-DMCs in the L1MdA subfamily