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Table 2 The number of DMCs commonly detected in the same positions in two independent experiments*

From: Acquired sperm hypomethylation by gestational arsenic exposure is re-established in both the paternal and maternal genomes of post-epigenetic reprogramming embryos

 

F1 Sperm

F1 Sperm (Exp. 1) &

F2 Embryo (Exp. 1)

F2 Embryo

HypoDMC

Exp. 1

2,837

F1 Sperm

2,742

Exp. 1

18,423

 

Exp. 2

1,503

F2 Embryo

17,648

Exp. 2

5,336

 

Common

21

Common

48

Common

165

HyperDMC

Exp. 1

690

F1 Sperm

572

Exp. 1

8,896

 

Exp. 2

402

F2 Embryo

8,670

Exp. 2

2,750

 

Common

0

Common

6

Common

85

  1. * CpGs that are common in 20 samples in the two experiments were selected using methylKit and DMCs (methylation difference ≥ 10% with q value < 0.01) were detected in the common CpGs for each experiment. The number of DMCs in the same positions and different positions between the two experiments are indicated. F1 sperm DMCs were obtained using the RRBS data of F1 sperm (GEO150650) and of another independent experiment (GSE150500) (Nohara et al. 2020)
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Epigenetics & Chromatin

ISSN: 1756-8935