Table 2 List of post-translational modification sites on TIP60 identified through various databases
Modification (Phosphorylation/Acetylation/SUMOylation/Ubiquitination) | Databases | ||
|---|---|---|---|
Phosphosite Plus https://www.phosphosite.org | BioGRID https://orcs.thebiogrid.org | ||
Phosphorylation | |||
S33 | - | ✓ | - |
Y44 | ✓ | - | - |
T77 | - | ✓ | - |
T79 | - | ✓ | - |
S86 | ✓ | ✓ | - |
S90 | ✓ | ✓ | - |
S98 | - | ✓ | - |
S102 | - | ✓ | - |
S155 | ✓ | ✓ | - |
T158 | ✓ | ✓ | ✓ |
S162 | - | ✓ | - |
T164 | - | ✓ | - |
S168 | - | ✓ | - |
S190 | ✓ | ✓ | - |
T195 | ✓ | ✓ | - |
S199 | ✓ | ✓ | - |
S202 | ✓ | ✓ | ✓ |
S203 | ✓ | ✓ | - |
S208 | - | ✓ | - |
T227 | ✓ | - | - |
T281 | ✓ | - | - |
Y294 | ✓ | - | - |
S431 | ✓ | - | - |
Y472 | ✓ | ✓ | - |
Acetylation | |||
K52 | ✓ | ✓ | - |
K76 | - | ✓ | - |
K80 | - | ✓ | - |
K104 | ✓ | ✓ | - |
K120 | ✓ | ✓ | - |
K148 | ✓ | ✓ | - |
K150 | ✓ | ✓ | - |
K187 | ✓ | ✓ | - |
K189 | ✓ | ✓ | - |
K268 | ✓ | ✓ | - |
K282 | ✓ | ✓ | - |
K327 | ✓ | ✓ | - |
K383 | - | ✓ | - |
K404 | - | ✓ | - |
SUMOylation | |||
K430 | ✓ | ✓ | - |
K451 | ✓ | ✓ | - |
Ubiquitination | |||
K35 | ✓ | ✓ | ✓ |
K230 | ✓ | - | ✓ |
K274 | ✓ | - | - |
K282 | ✓ | ✓ | ✓ |
K296 | ✓ | - | ✓ |
K310 | ✓ | - | ✓ |
K404 | ✓ | - | - |
K451 | - | - | ✓ |
K498 | ✓ | - | - |
K505 | ✓ | - | - |