Table 3 List of PTM sites on TIP60 reported as mutations in various cancer
S. No. | Mutations | Modification | Cancer | Reference (https://www.cbioportal.org/) |
|---|---|---|---|---|
1 | K35R | Ubiquitination | Head and neck squamous cell carcinoma | |
2 | T77A | Phosphorylation | Colorectal adenocarcinoma | |
3 | S155L | Phosphorylation | Cervical squamous cell carcinoma & Bladder urothelial carcinoma | |
4 | S190L | Phosphorylation | Pancreatic adenocarcinoma | |
5 | K274N | Ubiquitination | Liver hepatocellular carcinoma | |
6 | K310N | Ubiquitination | Ovarian serous cystadenocarcinoma & Skin cutaneous melanoma | |
7 | S431L | Phosphorylation | Uterine corpus endometrial carcinoma |