Fig. 3
From: Lysine crotonylation in disease: mechanisms, biological functions and therapeutic targets
Biological functions of protein Kcr in diseases. Kcr has been shown to regulate protein biological functions in various diseases, and abnormal Kcr levels closely linked to disease onset and progression. For instance, Kcr regulates gene transcription in colorectal cancer, mitophagy in NSCLC, and metabolic processes in OSCC. Furthermore, Kcr plays a key role in DNA damage repair, tumor immunity, and cell differentiation