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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: DNMT3B promotes the progression of pheochromocytoma by mediating the hypermethylation of LRP1B promoter

Fig. 2

The promoter of LRP1B was hypermethylated in pheochromocytoma. (A) RT-qCPR showing the mRNA level of LRP1B in adrenal medullary cells and pheochromocytoma cells (PC12), n=34. (B) Western blot showing the expression of LRP1B in cells. (C) Methprimer showing the predicted CpG islands in the promoter region of LRP1B; (D) MSP showing the methylation of LRP1B in pheochromocytoma cells. n=3. (A) MSP showing the methylation of LRP1B in Pheo and adjacent tissues. All results were analyzed by t test. n=4*P<0.05, **P<0.01, ***P<0.001.

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Epigenetics & Chromatin

ISSN: 1756-8935