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Epigenetics & Chromatin

Featured Articles 2025

H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation

byNew Content Item Kei Fukuda, Chikako Shimura & Yoichi Shinkai

“In this study, we successfully analysed the transcription, epigenome and 3D genome organization in mammalian cells that, for the first time, lacked all three major repressive chromatin modifications: H3K9 methylation, H3K27me3, and uH2A. Our findings revealed that, in the absence of H3K9 methylation, H3K27me3 and PRC1-uH2A can independently or some inter-dependently contribute to maintain gene/TE silencing and nuclear compartments”. Read full article here.

Function of HP1BP3 as a linker histone is regulated by linker histone chaperones, NPM1 and TAF-I

New Content Itemby Miharu Hisaoka, Tetsuro Komatsu, Takuma Hashimoto, Jianhuang Lin, Yasuyuki Ohkawa & Mitsuru Okuwaki

This study reveals that HP1BP3 binds NCPs in a manner similar to linker histone H1 and the linker histone function of HP1BP3 was found to be regulated by the linker histone chaperones, NPM1 and TAF-Iβ. The results of these study contribute to the understanding of the mechanisms by which linker histone variants regulate higher order chromatin structures. Read full article here.

Featured Articles from 2024

PRKACB is a novel imprinted gene in marsupials

by Trent Newman, Donna M. Bond, Teruhito Ishihara, Phoebe Rizzoli, Quentin Gouil, Timothy A. Hore, Geoff Shaw & Marilyn B. Renfree

TP63–TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer

by R. Sultanov, A. Mulyukina, O. Zubkova, A. Fedoseeva, A. Bogomazova, K. Klimina, A. Larin, T. Zatsepin, T. Prikazchikova, M. Lukina, M. Bogomiakova, E. Sharova, E. Generozov, M. Lagarkova & G. Arapidi

Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers

by Michael Camerino, William Chang & Ales Cvekl

Roles of post-translational modifications of UHRF1 in cancer

by Lili Gu, Yongming Fu & Xiong Li

From compartments to loops: understanding the unique chromatin organization in neuronal cells

by Diana Zagirova, Anna Kononkova, Nikita Vaulin & Ekaterina Khrameeva

CREdb: A comprehensive database of Cis-Regulatory Elements and their activity in human cells and tissues

by Chris Hartl, Jiali Zhuang, Aaron Tyler, Bing Zhou, Emily Wong, David Merberg, Brad Farrell, Chris DeBoever, Julie Bryant & Dorothée Diogo

The role of ribosomal DNA methylation in embryonic development, aging and diseases

by Fei Yang, Xutong Guo, Yiming Bao & Rujiao Li

H3.3K122A results in a neomorphic phenotype in mouse embryonic stem cells

by Benjamin J. Patty, Cailin Jordan, Santana M. Lardo, Kris Troy & Sarah J. Hainer

Calls for Papers:

Fundamentals and Perspectives in Epigenetics & Chromatin Research

Do you have an idea for a thematic series? Let us know!

Epigenetics & Chromatin especially welcomes submissions of original- or review- articles on high-impact topics within the journal’s scope. If you have any questions or suggestions, please contact us.

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Aims and scope

Epigenetics & Chromatin is a peer-reviewed, open access journal that publishes research, and reviews, providing novel mechanistic insights into epigenetic inheritance and chromatin-based interactions. The journal aims to understand how gene and chromosomal elements are regulated and their activities maintained during processes such as cell division, differentiation and environmental alteration.

This encompasses but is not limited to studies addressing:

  • Molecular processes and mechanisms, including histone modifications, DNA methylation and modification, structure and mechanism of epigenetic enzymes, regulation of gene expression, histone variants, linker histones.
  • Chromatin structure and dynamics, including structural and modelling studies, chromatin remodeling, nucleosome positioning, structure and mechanism of chromatin related enzymes and complexes, mechanisms of chromatin regulation, higher order chromatin structure.
  • Epigenetic processes, including genomic imprinting, dosis compensation and X-chromosome inactivation, mitotic & meiotic heritability of epigenetic information.
  • Development of new biochemical and computational tools and methods, including single cell epigenomics approaches, novel epigenome analysis methods, bioinformatic technologies in epigenomics research, epigenome editing, computational epigenomics.
  • Biological processes, including developmental epigenetics, cancer epigenetics, neuroepigenetics, non-coding RNA with roles in epigenetics and chromatin biology, plant epigenetics, epigenetics and metabolism, epigenetics and evolution.

Efficient peer review

Expedited: we recognise that scientifically sound, high quality manuscripts are often turned away from broad-scope "high-impact" journals based on the issue of "general interest." As a specialist journal, Epigenetics & Chromatin will consider rapid publication of such manuscripts if they are submitted as presubmission inquiries together with the original peer reviewer reports, letter of rejection, and a brief rebuttal.

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Find Best-Fit Journal for your article!

Choosing the right journal is essential for every author, and we are fully committed to collaborating across our prestigious epigenetics journals to assist you in this process. To facilitate an informed decision, we offer a concise overview of our three journals. For more detailed information on each one, simply click on the journal title below: 

New Content Item

•Epigenetics & Chromatin 

•Clinical Epigenetics

•Epigenetics Communications

Our dedicated Editors, with their extensive expertise in the field, will carefully evaluate your submission. If they believe that another journal within our network may better align with your research, they will propose a transfer during the peer-review process. This transfer will significantly expedite the handling of your submission, eliminating the need for additional peer-review rounds. We value your research and are here to support you every step of the way. Explore our options and make the most of our collaborative efforts to ensure your work reaches its full potential. 

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Affiliated with

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  • Epigenetics & Chromatin is affiliated with the International Society for Molecular and Clinical Epigenetics (isMOCLEP). isMOCLEP is open to all those interested in the wide spectrum of epigenetic research, from molecular to clinical aspects. isMOCLEP community welcomes academic researchers, early career scientists, companies, policy makers, and beyond.

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Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 4.2
    5-year Journal Impact Factor: 4.9
    Source Normalized Impact per Paper (SNIP): 0.892
    SCImago Journal Rank (SJR): 2.062

    Speed 2024
    Submission to first editorial decision (median days): 1
    Submission to acceptance (median days): 97

    Usage 2024
    Downloads: 690,485
    Altmetric mentions: 176

Epigenetics & Chromatin

ISSN: 1756-8935