Fig. 6

High reproducibility of pyrosequencing technical replicates in discovery and validation cohorts. Correlation plots showing the Pearson correlation between technical replicates for each cohort analyzed using pyrosequencing. Both the Discovery and Validation cohorts demonstrate near-perfect correlation, with Pearson correlation coefficients close to 1 and a highly significant P-value (< 2.2 × 10−16), confirming the high reproducibility of the analysis