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Table 1 Clinical characteristics of the study participants

From: DNA methylation signatures of severe RSV infection in infants: evidence from non-invasive saliva samples

 

Mild/moderate (n = 8)

Severe (n = 8)

P-value

Adjusted P-value

Age in years (mean)*

1.06 [0.67]

0.18 [0.11]

2.74 × 10–03

8.23 × 10−03

Sex

  

0.31

0.43

 Male

6 (75%)

3 (37%)

  

 Female

2 (25%)

5 (63%)

  

Self-reported ancestry

  

0.47

0.58

 South Europe

8 (100%)

6 (75%)

  

 North Africa

–

2 (25%)

  

Personal medical history

    

 Previous medical episode

6 (75%)

2 (25%)

0.13

0.25

 Previous episode of bronquiolitis

5 (63%)

–

0.03

0.06

Fever

5 (63%)

4 (50%)

1

1

Oxygen need

4 (50%)

8 (100%)

0.08

0.16

ReSViNET score*

7.60 [2.33]

15.86 [1.35]

2.77 × 10–06

4.16 × 10–05

Respiratory support

    

 Mechanical*

–

8 (100%)

1.55 × 10–04

5.83 × 10–04

Suspected bacterial infection

3 (37%)

4 (50%)

0.24

0.40

PICU*

–

8 (100%)

1.55 × 10–04

5.83 × 10–04

Antibiotic

4 (50%)

7 (88%)

0.28

0.42

Corticosteroids

5 (63%)

3 (37%)

0.62

0.66

Salbutamol

5 (63%)

3 (37%)

0.62

0.66

  1. Wilcoxon and t tests were used for comparison
  2. *Indicates the variables with a statistically significant difference (adjusted P-value) between the mild/moderate and severe groups