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Table 4 The clinical characteristics of mild/moderate and severe patients in the validation cohort

From: DNA methylation signatures of severe RSV infection in infants: evidence from non-invasive saliva samples

 

Mild/moderate (n = 7)

Severe (n = 7)

P-value

Adjusted P-value

Age in years (mean)*

1.06 [1.23]

0.27 [0.30]

0.14

0.25

Sex

  

0.46

0.72

 Male

7 (100%)

5 (72%)

  

 Female

–

2 (28%)

  

Self-reported ancestry

  

1

1

 South Europe

5 (72%)

5 (72%)

  

 North Africa

2 (28%)

2 (28%)

  

Personal medical history

    

 Previous medical episode

2 (28%)

1 (14%)

1

1

 Previous episode of bronquiolitis

2 (28%)

1 (14%)

1

1

Fever

4 (57%)

6 (86%)

0.56

0.78

Oxygen need

2 (28%)

7 (100%)

0.02

0.04

ReSViNET score*

6.14 [2.61]

16.43 [1.72]

4.31 × 10–06

6.03 × 10–05

Respiratory support

    

 Mechanical*

–

7 (100%)

5.80 × 10–04

2.71 × 10–03

Suspected bacterial infection

–

–

1.00

1.00

PICU*

–

7 (100%)

5.80 × 10–04

2.71 × 10–03

Antibiotic

1 (14%)

7 (100%)

0.01

0.01

Corticosteroids

2 (28%)

7 (100%)

0.02

0.04

Salbutamol

1 (14%)

7 (100%)

0.01

0.01

  1. *Indicates the variables with a statistically significant difference (adjusted P-value) between the mild/moderate and severe groups